Peer-reviewed veterinary case report
Successful treatment of ethylene glycol poisoning in cats
By Tart, Kelly M & Powell, Lisa L·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2011·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: 4-Methylpyrazole as a treatment in naturally occurring ethylene glycol intoxication in cats.
- Species:
- cat
Plain-English summary
Three cats were treated for ethylene glycol (antifreeze) poisoning after testing positive for the toxin. They received an intravenous treatment called fomepizole (4-methylpyrazole), which was given in specific doses over a 36-hour period. All three cats recovered and were discharged from the hospital after treatment. This case shows that fomepizole is a safe and effective option for treating ethylene glycol poisoning in cats.
People also search for: cat antifreeze poisoning treatment · ethylene glycol toxicity in cats · fomepizole for cats
Abstract
OBJECTIVE: To describe the clinical experience and therapeutic use of fomepizole (4-methylpyrazole [4-MP]) in 3 cats with naturally occurring ethylene glycol (EG) toxicity. CASE OR SERIES SUMMARY: All cats were documented to be EG positive by an ethylene glycol test kit. This report describes the dose of 4-MP used, available clinicopathological data, and clinical progression during hospitalization. All patients survived to discharge. NEW OR UNIQUE INFORMATION PROVIDED: IV use of 4-MP at 125 mg/kg as an initial dose and 31.25 mg/kg at 12, 24, and 36 hours is safe and effective for treatment of naturally occurring EG toxicity in cats. Increased HCO₃ concentrations were noted after IV use of 4-MP. This is the first report documenting the successful treatment of naturally occurring EG intoxication in cats with 4-MP.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21631713/