Peer-reviewed veterinary case report
A 3-Year Case Report on an Atopic Patient with a Caninised Monoclonal Antibody Treatment
- Journal:
- Folia Veterinaria
- Year:
- 2022
- Authors:
- Petrou P.
- Affiliation:
- Heath and Reach Veterinary Surgery, Kingswood Farm, Brickhill Road, Heath and Reach, Leighton Buzzard, LU7 0BA, United Kingdom · PL
- Species:
- dog
Plain-English summary
A 6-year-old male English Mastiff was taken to a vet for a second opinion because he had been dealing with severe itching for a long time. He had been on medications for four years to help with his skin issues. After various tests, the vet confirmed he had canine atopic dermatitis, which is a common allergic skin condition in dogs. The dog was treated with a new medication called lokivetmab, along with other treatments during flare-ups to help control his symptoms. Overall, the treatment worked well over the three years, improving his condition significantly.
Abstract
A 6-year-old, male, neutered, English Mastiff dog was presented for a second opinion due to chronic pruritus. The patient had been on methylprednisolone and chlorphenamine for four years. The diagnostic investigations included: swabs for bacterial and mycology culture, hair plugs for dermatophyte culture, acetate tape strips and deep skin scrapes, skin biopsies for dermatohistopathology, biochemistry, haematology, endocrinology, serology for canine scabies using enzyme-linked immunosorbent assay (ELISA) testing and serology for allergen specific IgE antibodies. The history and the diagnostics confirmed the diagnosis of canine atopic dermatitis. This case report details the treatment with lokivetmab, which is a caninised monoclonal antibody drug. At periods of flare ups, additional treatments were prescribed, such as systemic glucocorticoids and oclacitinib in order to manage the clinical signs. The treatment showed good response to the overall treatment management during the three year period of this atopic patient.
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Search related cases →Original publication: https://doi.org/10.2478/fv-2022-0005