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Peer-reviewed veterinary case report

A brief report of basic science: the effects of preincisional low-dose ketamine on natural killer cell activity in male Fischer 344 rats after intra-abdominal surgery.

Journal:
Dimensions of critical care nursing : DCCN
Year:
2009
Authors:
Estes, Savannah et al.
Affiliation:
US Army Graduate Program in Anesthesia Nursing · United States
Species:
rodent

Abstract

Although the first line of defense in cancer treatment often is surgery, studies suggest that postoperative pain and anesthetic drugs suppress the activity of cells that lyse metastatic cells, that is, natural killer cells. We assessed the affect of low-dose ketamine on natural killer cell activity. The findings are presented in this brief report.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19104252/