Peer-reviewed veterinary case report
Dog with large tumor in right atrium causing loss of appetite
By Yanagawa, Hirotaka et al.·Published in The Journal of veterinary medical science·2014·School of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: A canine case of primary intra-right atrial paraganglioma.
- Species:
- dog
Plain-English summary
An 11-year-old mixed breed dog was brought to the vet because it wasn't eating. Tests including X-rays and ultrasounds showed a large tumor in the heart, specifically in the right atrium. The tumor was identified as a paraganglioma, which is a type of growth that can affect hormone production. Unfortunately, the abstract does not provide information on treatment or the outcome for this dog.
People also search for: dog heart tumor symptoms · why is my dog not eating · paraganglioma in dogs treatment
Abstract
An 11-year-old mixed breed dog was presented with signs of anorexia. Radiographic and ultrasound examinations revealed a large mass in the heart, between the right atrium and the right ventricle. Upon gross inspection, a multilobulated tumor arising from the right atrial wall and occupying the right atrium was identified. Microscopical analysis demonstrated that this tumor consisted of neoplastic cells with granular cytoplasm, which were separated into nests by fine fibrovascular stroma and were negative for Grimelius's method. Immunohistochemical examinations revealed that the neoplastic cells expressed chromogranin A, synaptophysin and neuron specific enolase. Electron microscopy revealed that the cytoplasm of the neoplastic cells held secretory granules. Based on these pathological findings, the tumor was diagnosed as a paraganglioma. This report is a rare case of primary paraganglioma deriving from the right atrium and provides a detailed characterization of its morphological features.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24670962/