Peer-reviewed veterinary case report
Miniature Schnauzer with skull tumor treated by hydroxyurea
By Tamura, Shinji et al.·Published in The Journal of veterinary medical science·2007·Tamura Animal Clinic, Japan·View original on PubMed →
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Original publication title: A canine case of skull base meningioma treated with hydroxyurea.
- Species:
- dog
Plain-English summary
An 11-year-old female miniature schnauzer was diagnosed with a skull base meningioma (a type of brain tumor) after several tests. Because surgery was too risky and radiation therapy wasn't available, the vet started her on chemotherapy with hydroxyurea and dexamethasone. After just one week, her symptoms improved, and follow-up imaging showed the tumor had shrunk. She continued treatment for seven months, during which her condition remained stable, but the tumor eventually grew back. Sadly, she passed away from pulmonary edema (fluid in the lungs) 14 months after starting treatment.
People also search for: miniature schnauzer brain tumor treatment · hydroxyurea for dogs · dog meningioma symptoms
Abstract
An 11-year-old female miniature schnauzer was tentatively diagnosed with the skull base meningioma, based on several examinations. Because surgical treatment was difficult, and outpatient radiation therapy was not available in the local area, chemotherapy with hydroxyurea combined with dexamethasone was selected. The patient's clinical symptoms improved after one week of treatment, and the tumor size was obviously reduced on MRI performed 37 days after treatment began. The patient received hydroxyurea for 7 months, with symptoms remaining stable, and the tumor re-increased to almost the same size at 7 months as that at the initial examination. At that time, hydroxyurea was discontinued. The patient died from pulmonary edema 14 months after treatment began. Pathologically, the tumor was diagnosed as a meningioma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18176033/