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Peer-reviewed veterinary case report

Nerve sheath tumor with nerve fibers found in a dog's cheek

By Sawamoto, O et al.·Published in The Journal of veterinary medical science·1999·Department of Veterinary Pathology, Japan·View original on PubMed

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Original publication title: A canine peripheral nerve sheath tumor including peripheral nerve fibers.

Species:
dog

Plain-English summary

A 7-year-old male mongrel dog was diagnosed with a tumor in the right cheek and mouth area, which was affecting the surrounding nerve fibers. The tumor was identified as a peripheral nerve sheath tumor, a type of growth that can develop around nerves. The dog's condition was evaluated through various tests, including a biopsy, which showed that the tumor cells had specific characteristics. While the abstract does not mention treatment details, tumors like this may require surgical removal. It's important for pet owners to consult their veterinarian for the best course of action if they notice unusual growths or swelling in their dog's mouth or face.

People also search for: dog mouth tumor · cheek swelling in dogs · canine peripheral nerve sheath tumor treatment

Abstract

Peripheral nerve sheath tumor was found in a 7-year-old male mongrel dog. The tumors were located in the right cheek subcutis and oral submucosa. Histologically, neoplastic cells were arranged in streaming bundles, occasionally interlacing bundles or whorls of elongated and spindle cells. Cellular atypia was poor and mitotic figures were rarely observed. Ultrastructurally, neoplastic cells had basement membrane, typical of Schwann cells. One bundle of normal peripheral nerve fibers and some myelinated axons were seen within the tumor tissues. Immunohistochemically, neoplastic cells reacted to vimentin, glial fibrillary acidic protein, S-100 protein and neuron specific enolase. In addition to the above immunoreactions, the included nerve fibers were positive for myelin basic protein and neurofilament protein. This paper also discusses immunohistochemical findings on differential diagnosis in comparison with those of canine hemangiopericytomas reported hitherto.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10651057/