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Peer-reviewed veterinary case report

Carcinoid tumor found in gallbladder of 10-year-old dog

By Morrell, C N et al.·Published in Veterinary pathology·2002·View original on PubMed

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Original publication title: A carcinoid tumor in the gallbladder of a dog.

Species:
dog

Plain-English summary

A 10-year-old spayed female mixed-breed dog was brought to the vet due to chronic weight loss and elevated liver enzymes. An ultrasound showed an enlarged gallbladder, leading to surgery to remove it. After the operation, the dog was diagnosed with a rare type of tumor called a biliary carcinoid. While these tumors are uncommon in pets, the surgery was necessary for her health.

People also search for: dog weight loss gallbladder tumor · mixed-breed dog liver problems · dog surgery for gallbladder issues

Abstract

A cholecystectomy was performed on a 10-year-old spayed female mixed-breed dog with chronic weight loss, persistently increased liver enzyme activities, and cholecystomegaly identified by ultrasonographic examination. A subsequent diagnosis of a biliary carcinoid was made based on a neuroendocrine-type histologic pattern, cytoplasmic argyrophilia by Grimelius staining, immunopositivity for chromogranin A, and the ultrastructural finding of cytoplasmic secretory granules in neoplastic cells. Extrahepatic biliary carcinoid tumors are rare tumors of humans and have not been documented in domestic animals.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12450211/