Peer-reviewed veterinary case report
Yorkshire terrier with adrenal gland disease treated with mitotane
By Lee, Young-Mi et al.·Published in Journal of veterinary science·2005·Department of Veterinary Internal Medicine, South Korea·View original on PubMed →
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Original publication title: A case of adrenal gland dependent hyperadrenocorticism with mitotane therapy in a Yorkshire terrier dog.
- Species:
- dog
Plain-English summary
A 10-year-old male Yorkshire terrier was brought in for corneal ulcers (sores on the eye) and hair loss all over his body. After a thorough examination and tests, the vet diagnosed him with a condition called hyperadrenocorticism, which means his body was producing too much cortisol due to a problem with his adrenal glands. The treatment involved a medication called mitotane, which helps reduce cortisol levels. After starting the treatment, the dog's condition improved, and he continued on mitotane for maintenance therapy to keep his cortisol levels in check.
People also search for: dog hair loss treatment · Yorkshire terrier eye problems · mitotane for dog hyperadrenocorticism
Abstract
Hyperadrenocorticism, a disorder characterized by excessive production of cortisol by the adrenal cortex, is well-recognized in dogs. A 10-year-old, intact male, Yorkshire terrier dog was evaluated because of corneal ulceration and generalized alopecia. Diagnosis was made based on history taking, clinical signs, physical examination, and results of routine laboratory testing (complete blood count, serum biochemical analysis, and urinalysis). In addition, adrenocorticotropic hormone (ACTH) stimulation test and abdominal ultrasonography were also used to diagnose this case. The patient was diagnosed as adrenal gland neoplasia and medical therapy using the adrenocorticolytic agent, mitotane, was initiated. An ACTH stimulation test was performed after initial therapy. After successful induction was obtained, maintenance therapy with mitotane still continued.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16294004/