Peer-reviewed veterinary case report
Dog with nasal Aspergillus infection spreading to brain and muscle
By Cox, Sarah E et al.Ā·Published in Veterinary medicine and scienceĀ·2025Ā·Department of Veterinary Medicine, United KingdomĀ·View original on PubMed ā
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Original publication title: A Case of Canine Sinonasal Aspergillus fumigatus Infection Associated With Intracranial Extension and Temporal Myositis.
- Species:
- dog
Plain-English summary
A 12-year-old terrier was brought in for coughing, sneezing, and a runny nose that had lasted for four months. The vet found that the dog had a fungal infection in the nasal area, which had spread to the brain. After a procedure to clean out the infection and starting antifungal medications, the dog's condition improved. Although some issues remained, including a persistent nasal discharge, the dog has been doing well for four months with ongoing treatment.
People also search for: dog coughing sneezing runny nose Ā· terrier nasal infection treatment Ā· canine fungal infection symptoms
Abstract
A 12-year-old terrier was referred for investigation of a 4-month history of coughing, sneezing and nasal discharge. Clinical findings were consistent with sinonasal Aspergillus fumigatus infection with evidence of intracranial extension on computed tomography. Endoscopic debridement followed by topical clotrimazole and systemic antifungal therapy resulted in clinical improvement. Magnetic resonance imaging after 4 weeks showed reduced intracranial disease but demonstrated evidence of temporal myositis. Repeated debridement and topical treatment were performed at 4 and 8 weeks in conjunction with long-term voriconazole therapy. Further interventions were declined; the dog remains clinically well after 4 months with unilateral nasal discharge. As in human patients, invasive subtypes of sinonasal aspergillosis may also occur in dogs and be associated with poorer response to treatment.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39740066/