Peer-reviewed veterinary case report
Ulcerative skin nodules in a Maltese dog
By Kawarai, Shinpei et al.·Published in Journal of the American Animal Hospital Association·2014·Veterinary Teaching Hospital Laboratory of Small Animal Clinics (S.K., Japan·View original on PubMed →
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Original publication title: A case of cutaneous sterile pyogranuloma/granuloma syndrome in a maltese.
- Species:
- dog
Plain-English summary
A 5-year-old Maltese was brought in for severe skin problems, including painful ulcers all over its body, along with signs of mild anemia. After testing, the vet diagnosed the dog with cutaneous sterile pyogranuloma/granuloma syndrome, a condition that causes inflammation in the skin. The treatment involved long-term use of immunosuppressive medications, specifically prednisolone and azathioprine, which helped control the symptoms. However, the dog experienced flare-ups when the medications were stopped, indicating that ongoing treatment may be necessary for managing this condition effectively.
People also search for: Maltese skin problems · dog ulcerative dermatitis treatment · immunosuppressive drugs for dogs
Abstract
Cutaneous sterile pyogranuloma/granuloma syndrome (SPGS) is a locally restricted multinodular dermatitis. Affected dogs are typically healthy, but a few show systemic signs. Herein, a case of a dog presenting with generalized ulcerative dermatitis with systemic signs of mild anemia and an increased C-reactive protein level is described. Cutaneous SPGS was diagnosed by histopathology, negative staining causative organisms, and polymerase chain reaction for Mycobacterium spp. Successful treatment was achieved by immunosuppressive drugs, including prednisolone and azathioprine, administered for at least 20 mo. Recurrences of skin lesions were observed when prednisolone and/or azathioprine were discontinued. Long-term management with immunosuppressive agents may be required if the affected dog exhibits severe symptoms of cutaneous SPGS.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24855086/