A Case of Dystrophic Epidermolysis Bullosa Treated with Meek Technique and Cultured Epithelial Autografts.

Abstract

Dystrophic epidermolysis bullosa (DEB) causes extensive blisters and erosions due to a genetic abnormality, significantly reducing patients' quality of life. Recently, transplantation of reversion-mutated mosaicized skin has shown promise as a radical cure. In 2019, the use of cultured epithelial autograft for DEB was approved in Japan. Meanwhile, the Meek micrografting technique, first described in 1958 by Dr. Cicero Parker Meek in the United States of America, was reintroduced in 2019 as a new device for split-thickness skin grafting. This system can harvest skin grafts more efficiently than conventional methods. In this case report, we report on our successful treatment of DEB using the Meek technique and cultured epithelial autografts.