Peer-reviewed veterinary case report
Young Cane Corso dog brain tumor spread to lungs case
By Van de Weyer, Yannick et al.·Published in Journal of comparative pathology·2024·Institute of Infection, United Kingdom·View original on PubMed →
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Original publication title: A case of epithelioid glioblastoma with lung metastases in a young Cane Corso dog.
- Species:
- dog
Plain-English summary
A young Cane Corso was diagnosed with a brain tumor called glioblastoma, which is a type of cancer that can spread to other parts of the body, including the lungs. This dog showed signs of illness, and tests revealed the tumor's aggressive nature. The diagnosis was confirmed through specialized lab tests that looked at the tumor's characteristics. Unfortunately, this type of cancer is very serious and can be difficult to treat effectively. The case highlights the rarity of this condition in dogs, especially with lung metastases.
People also search for: Cane Corso brain tumor symptoms · dog glioblastoma treatment · young dog lung cancer signs
Abstract
Astrocytomas are relatively common primary brain tumours of humans and companion animals. In dogs, they represent approximately 17-28% of primary central nervous system tumours. However, extracranial metastasis is extremely rare. This case report describes a grade IV astrocytoma (glioblastoma) in the cerebrum of a young Cane Corso dog with pulmonary metastases. The diagnosis was obtained via histopathological morphology and immunophenotyping, which showed strong positivity for glial fibrillary acidic protein, vimentin and connexin-43. The glioblastoma in this Cane Corso had epithelioid morphology with histological features of malignancy including high mitotic count, microvascular proliferation, serpentine necrosis and subventricular zone involvement. Epithelioid glioblastoma is a rare subtype that has only relatively recently been formally acknowledged in human medicine and it can also pose a diagnostic challenge in veterinary medicine.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39442362/