Peer-reviewed veterinary case report
Cat with duodenal mass and vomiting cured by steroids
By Mario Pultrone et al.·Published in Animals·2025·Anicura Policlinico Veterinario Roma Sud, 00173 Rome, Italy, CH·View original on DOAJ →
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Original publication title: A Case of Feline Eosinophilic Sclerosing Fibroplasia Associated with a Duodenal Mass Responsive to Exclusive Glucocorticoid Therapy
- Species:
- cat
Plain-English summary
A 6-year-old female European Shorthair cat was brought to the vet for chronic vomiting and weight loss. After an endoscopy, the vet found a mass in her intestine and diagnosed her with a rare condition called eosinophilic sclerosing fibroplasia. The cat was treated with a steroid medication called prednisolone, which led to a complete recovery in just 15 days. Follow-up tests showed that the mass was gone, and the cat has been doing well for over a year, with no major issues since adjusting her medication dosage.
People also search for: cat vomiting weight loss · feline eosinophilic sclerosing fibroplasia treatment · prednisolone for cats
Abstract
This report describes a case of feline gastrointestinal eosinophilic sclerosing fibroplasia (FGESF) in a 6-year-old spayed female European Shorthair cat presenting with chronic vomiting and weight loss. Endoscopic examination revealed a submucosal duodenal mass, and histopathological evaluation of endoscopic biopsies confirmed a diagnosis of FGESF. The cat was treated exclusively with oral prednisolone (1 mg/kg SID), leading to complete clinical remission within 15 days. Follow-up ultrasonography and endoscopy performed 30 days later confirmed full resolution of the mass, which was replaced by a focal mucosal depression. Histopathology at that site revealed chronic-active lymphoplasmacytic and neutrophilic enteritis with mild fibroplasia. A mild recurrence of duodenal thickening was observed after steroid tapering, which resolved upon dosage adjustment. The patient has remained clinically stable for 15 months with normal imaging and blood parameters.
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Search related cases →Original publication on DOAJ: https://doi.org/10.3390/ani15192888