Peer-reviewed veterinary case report
A case of feline gastrointestinal eosinophilic sclerosing fibroplasia mimicking metastatic neoplasia.
- Journal:
- New Zealand veterinary journal
- Year:
- 2014
- Authors:
- Munday, J S et al.
- Affiliation:
- Institute of Veterinary
- Species:
- cat
Plain-English summary
A 7-year-old cat started having occasional vomiting, eating less than usual, and losing weight over the last three months. During a check-up, the vet found a large mass in the cat's abdomen, and the cat continued to lose weight over the next seven weeks until it was put to sleep. An examination after death showed a firm white mass in the colon and another in the stomach area, along with swollen lymph nodes. The findings indicated a condition called gastrointestinal eosinophilic sclerosing fibroplasia (FGESF), which is a type of inflammation in the intestines. This case is significant because it's the first report of FGESF in a cat from New Zealand, and it suggests that FGESF may have a better outlook than similar intestinal tumors.
Abstract
CASE HISTORY: A 7-year-old cat developed sporadic vomiting, reduced appetite, and weight loss over the previous 3 months. CLINICAL FINDINGS: Palpation revealed a large mid-abdominal mass and the cat had marked eosinophilia. The cat progressively lost weight over the next 7 weeks when euthanasia was performed. PATHOLOGICAL FINDINGS: Necropsy revealed a 3 cm diameter firm white intramural mass in the colon and another in the pylorus. Mesenteric and cranial mediastinal lymph nodes were firm, pale, and enlarged. Histopathological examination revealed foci of necrosis surrounded by thick dense collagen trabeculae and predominantly eosinophilic inflammation within the intestine and lymph nodes. Marked eosinophilic infiltration of the liver was also present. DIAGNOSIS: The lesions were consistent with gastrointestinal eosinophilic sclerosing fibroplasia (FGESF). CLINICAL RELEVANCE: This is the first report of FGESF in a New Zealand cat and the first time lesions of FGESF have been observed in extra-abdominal tissues. Intestinal neoplasia can be clinically identical to FGESF and histopathology is required for differentiation. Evidence suggests that FGESF has a more favourable prognosis than intestinal neoplasia.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24926904/