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Peer-reviewed veterinary case report

Cat with vomiting and weight loss had intestinal eosinophilic

By Munday, J S et al.·Published in New Zealand veterinary journal·2014·Institute of Veterinary·View original on PubMed

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Original publication title: A case of feline gastrointestinal eosinophilic sclerosing fibroplasia mimicking metastatic neoplasia.

Species:
cat

Plain-English summary

A 7-year-old cat started vomiting sporadically, had a reduced appetite, and lost weight over three months. A vet found a large mass in the cat's abdomen, and despite treatment, the cat continued to lose weight and was eventually euthanized. A necropsy revealed a firm mass in the colon and another in the stomach, along with inflammation in the liver and lymph nodes. The diagnosis was gastrointestinal eosinophilic sclerosing fibroplasia, a condition that can mimic cancer but generally has a better outlook. Unfortunately, in this case, the cat did not recover.

People also search for: cat vomiting weight loss · cat abdominal mass treatment · eosinophilic sclerosing fibroplasia cat

Abstract

CASE HISTORY: A 7-year-old cat developed sporadic vomiting, reduced appetite, and weight loss over the previous 3 months. CLINICAL FINDINGS: Palpation revealed a large mid-abdominal mass and the cat had marked eosinophilia. The cat progressively lost weight over the next 7 weeks when euthanasia was performed. PATHOLOGICAL FINDINGS: Necropsy revealed a 3 cm diameter firm white intramural mass in the colon and another in the pylorus. Mesenteric and cranial mediastinal lymph nodes were firm, pale, and enlarged. Histopathological examination revealed foci of necrosis surrounded by thick dense collagen trabeculae and predominantly eosinophilic inflammation within the intestine and lymph nodes. Marked eosinophilic infiltration of the liver was also present. DIAGNOSIS: The lesions were consistent with gastrointestinal eosinophilic sclerosing fibroplasia (FGESF). CLINICAL RELEVANCE: This is the first report of FGESF in a New Zealand cat and the first time lesions of FGESF have been observed in extra-abdominal tissues. Intestinal neoplasia can be clinically identical to FGESF and histopathology is required for differentiation. Evidence suggests that FGESF has a more favourable prognosis than intestinal neoplasia.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24926904/