Peer-reviewed veterinary case report
Cat with intestinal large granular lymphocyte lymphoma cured
By Akiyoshi, Makoto & Akiyoshi, Masami·Published in Veterinary medicine and science·2021·Akiyoshi Animal Clinic, Japan·View original on PubMed →
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Original publication title: A case of feline large granular lymphocyte lymphoma with complete remission and long survival by surgical resection and adjuvant nimustine administration.
- Species:
- cat
Plain-English summary
A 7-year-old spayed female Scottish Fold cat was brought to the vet after losing weight, not eating, and vomiting for four weeks. An ultrasound showed a mass in her intestines, which was diagnosed as a type of cancer called large granular lymphocyte lymphoma. The mass was surgically removed, and the cat then received chemotherapy with nimustine, along with other medications. After 18 treatments over 552 days, the cat is doing well, with no signs of the cancer returning.
People also search for: cat vomiting weight loss · Scottish Fold lymphoma treatment · nimustine for cat cancer
Abstract
A 7-year-old spayed female Scottish Fold cat presented with a 4-week history of anorexia, weight loss and vomiting. Abdominal ultrasonography revealed a jejunal mass and a slightly enlarged jejunal lymph node. A fine-needle aspiration of the mass revealed many round cells with multiple small intracytoplasmic magenta granules. The mass was diagnosed as a large granular lymphocyte (LGL) lymphoma based on cytology. The LGL lymphoma was completely resected via open surgery. The histologic and cytologic evaluations showed no neoplastic findings in the jejunal lymph node, liver, spleen, kidney or bone marrow. The LGL lymphoma was localized to the jejunum. Postoperatively, the cat received chemotherapy with nimustine, L-asparaginase and prednisolone. The cat is currently receiving nimustine every 6 weeks, without adverse events, and treatment has been administrated a total of 18 times up until day 552. The cat is in a good condition, and the LGL lymphoma has not recurred. Nimustine should be considered one of the effective chemotherapeutic agents in the treatment of feline LGL lymphoma cases in the future.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34405564/