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Peer-reviewed veterinary case report

Vomiting and weight loss from gastrinoma in a Shih-Tzu dog

By Fukushima, Ushio et al.·Published in The Journal of veterinary medical science·2004·Veterinary Teaching Hospital, Japan·View original on PubMed

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Original publication title: A case of gastrinoma in a Shih-Tzu dog.

Species:
dog

Plain-English summary

A 5-year-old male Shih-Tzu was brought in for severe vomiting and weight loss. Initially, the vet treated him with medications to reduce stomach acid, protect the gut, and fight infection, which helped for a short time. However, the vomiting returned after ten days, prompting further tests and surgery. During the operation, the vet found swollen areas in the pancreas, and a biopsy confirmed a gastrinoma, which is a rare tumor that produces excess gastrin hormone. The diagnosis was made, and the vet will discuss treatment options moving forward.

People also search for: Shih-Tzu vomiting treatment · dog weight loss causes · gastrinoma in dogs · pancreatic tumor symptoms in dogs

Abstract

A five-year-old male Shih-Tzu dog presented with severe vomiting and weight loss. The clinical signs were successfully improved by an eight-day treatment with an H(2)-receptor antagonist, gastrointestinal protectant and antibiotics. Ten days later, however, recurrence of vomiting was seen despite continuous medical treatment. Based on clinical signs and the results of various diagnostic tests including CBC, biochemical analysis, contrast radiography, and endoscopy, a duodenal or pancreatic neoplasm was suspected and exploratory laparotomy was conducted. Some swollen pancreatic regions were found, and biopsy of the pancreas indicated the diagnosis of a gastrin-secreting tumor. Consequently, based on a high serum gastrin level as well as clinical signs and immunohistological findings, we diagnosed the disease as canine gastrinoma, a rare tumor of the pancreas.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15107564/