Peer-reviewed veterinary case report
A case of gastrinoma in a Shih-Tzu dog.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2004
- Authors:
- Fukushima, Ushio et al.
- Affiliation:
- Veterinary Teaching Hospital · Japan
- Species:
- dog
Plain-English summary
A five-year-old male Shih-Tzu was brought to the vet because he was vomiting a lot and losing weight. After eight days of treatment with medications to reduce stomach acid, protect the stomach lining, and fight infection, his symptoms got better. Unfortunately, ten days later, he started vomiting again even while still on medication. The vet ran several tests, including blood work and imaging, and suspected a tumor in the pancreas or duodenum (the first part of the small intestine). An operation was performed, and a biopsy confirmed that he had a gastrinoma, which is a rare type of tumor that produces a hormone called gastrin.
Abstract
A five-year-old male Shih-Tzu dog presented with severe vomiting and weight loss. The clinical signs were successfully improved by an eight-day treatment with an H(2)-receptor antagonist, gastrointestinal protectant and antibiotics. Ten days later, however, recurrence of vomiting was seen despite continuous medical treatment. Based on clinical signs and the results of various diagnostic tests including CBC, biochemical analysis, contrast radiography, and endoscopy, a duodenal or pancreatic neoplasm was suspected and exploratory laparotomy was conducted. Some swollen pancreatic regions were found, and biopsy of the pancreas indicated the diagnosis of a gastrin-secreting tumor. Consequently, based on a high serum gastrin level as well as clinical signs and immunohistological findings, we diagnosed the disease as canine gastrinoma, a rare tumor of the pancreas.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15107564/