Peer-reviewed veterinary case report
West Highland White Terrier skin disease cured by interferon-gamma
By Nishifuji, Koji et al.·Published in The Journal of veterinary medical science·2007·Department of Dermatology, Japan·View original on PubMed →
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Original publication title: A case of hyperplastic dermatosis of the West Highland White Terrier controlled by recombinant canine interferon-gamma therapy.
- Species:
- dog
Plain-English summary
A 3.5-year-old male West Highland White Terrier was brought in for skin problems caused by hyperplastic dermatosis, which led to thickened and inflamed skin. Initially, antifungal medications helped a bit by reducing a yeast overgrowth, but the skin condition worsened again within two months. The vet then started treatment with a special medication called recombinant canine interferon-gamma, which nearly cleared up the skin lesions within two months without any side effects. This treatment shows promise as a new option for managing this specific skin disease in West Highland White Terriers.
People also search for: West Highland White Terrier skin problems · hyperplastic dermatosis treatment · dog interferon therapy · antifungal for dog skin issues · dog skin lesions treatment
Abstract
A 3.5-year-old, male West Highland White Terrier was diagnosed as having hyperplastic dermatosis by clinical and histopathological findings. Controlling of Malassezia overgrowth by antifungal drugs provided a temporal improvement of the skin lesions, but the disease was deteriorated within the next 2 months despite the negative demonstration of the yeasts. Induction of recombinant canine interferon-gamma (rCaIFN-gamma) therapy resulted in almost complete cure of the skin lesions within 2 months after the initiation of the therapy. No adverse effects were detected during the therapy. Our results suggested that the rCaIFN-gamma therapy is potential to be a novel therapeutic option for controlling the breed-specific hyperplastic skin disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17485941/