Peer-reviewed veterinary case report
Dog with skin cyst showing squamous cells eating neutrophils
By Nakayama, Hiroyuki et al.·Published in Journal of comparative pathology·2023·Animal Medical Center Peco, Japan·View original on PubMed →
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Original publication title: A case of infundibular cyst with neutrophil cannibalism by squamous cells in a dog.
- Species:
- dog
Plain-English summary
A 6-year-old neutered male mongrel dog had a noticeable skin mass between his left eye and nose. A biopsy of the mass showed unusual giant cells that contained many neutrophils, which are a type of white blood cell. The mass was surgically removed and diagnosed as an infundibular cyst, a type of skin cyst. After the surgery, the dog recovered well, and the cyst was successfully treated.
People also search for: dog skin mass near eye · infundibular cyst in dogs · treatment for dog skin lumps
Abstract
A 6-years and 6-months-old, neutered male mongrel dog had a skin mass between the left eye and nose. Fine needle aspiration biopsy of the mass revealed giant epithelial cells containing many neutrophils in the cytoplasm. The mass was excised and histopathologically diagnosed as an infundibular cyst with giant epithelial-like cells containing neutrophils in part of the lumen. The giant cells were immunopositive for cytokeratin and immunonegative for vimentin. Cell cannibalism is a cell engulfing phenomenon in which a cell incorporates either the same or a different type of cell and the incorporated cells are degenerate or necrotic. In this case, epithelial cells in the lumen of the cyst incorporated neutrophils, which corresponds to neutrophil cannibalism by squamous epithelial cells.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37866218/