Peer-reviewed veterinary case report
Young Papillon dog with lung hypertension treated long-term
By Toyoshima, Yumiko et al.·Published in The Journal of veterinary medical science·2007·Toyoshima Animal Hospital, Japan·View original on PubMed →
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Original publication title: A case of long-term sildenafil therapy in a young dog with pulmonary hypertension.
- Species:
- dog
Plain-English summary
A 7-month-old male Papillon was brought in because he was having trouble breathing, appeared blue in color, and had a heart murmur. Tests showed he had severe pulmonary hypertension (high blood pressure in the lungs), so the vet started him on sildenafil, a medication that helps improve blood flow. After four weeks of treatment, the dog's breathing and exercise ability improved significantly, and he continued to do well over the next four years without any side effects. The sildenafil helped him maintain a good quality of life throughout this time.
People also search for: dog breathing problems · Papillon pulmonary hypertension treatment · sildenafil for dogs · dog heart murmur symptoms
Abstract
A 7-month-old male Papillon was presented to us with mild dyspnea, cyanosis and a diastolic murmur detected by cardiac auscultation. Echocardiography revealed severe pulmonary arterial hypertension (PH), and administration of 1 mg/kg of oral sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, twice daily was initiated. Exercise capacity, cyanosis, dyspnea and cardiac murmur were improved after therapy for 4 weeks. PCV was remarkably high (74%) after therapy for 3 years, however, increasing the dose of sildenafil decreased this value (60%). Follow-up after therapy for 4 years revealed that treatment with oral sildenafil only continued to provide the dog with an excellent quality of life, without any side effects.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17984597/