Peer-reviewed veterinary case report
Miniature Dachshund recovers from severe destructive cholangitis
By Osumi, Takafumi et al.·Published in The Journal of veterinary medical science·2011·Department of Veterinary Internal Medicine, Japan·View original on PubMed →
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Original publication title: A case of recovery from canine destructive cholangitis in a Miniature Dachshund.
- Species:
- dog
Plain-English summary
A 7-year-old Miniature Dachshund was brought in with severe jaundice (yellowing of the skin and eyes) and high liver enzyme levels. After diagnosing destructive cholangitis (a liver condition), the vet started treatment with medications including prednisolone, high-dose ursodeoxycholic acid, human placental extract, and antibiotics. The dog showed signs of recovery after three months of treatment. A follow-up liver biopsy a year later confirmed some improvement, suggesting that with ongoing supportive care, dogs can recover from this serious liver condition.
People also search for: dog jaundice treatment · Miniature Dachshund liver disease · cholangitis in dogs recovery
Abstract
A 7-year-old Miniature Dachshund presented with severe chronic jaundice and elevated liver enzymes. Destructive cholangitis was diagnosed according to histopathological findings of remarkable ductopenia with inflammatory infiltrates and fibrosis in the portal areas. Supportive therapy with prednisolone, high-dose ursodeoxycholic acid, human placental extract and antibiotics was tried, and the patient showed recovery of clinical signs 3 months after diagnosis. A second liver biopsy was performed about 1 year after initial diagnosis, and bile duct restoration was confirmed with continuous inflammation around portal areas and inside the lobules. Although we could not determine which treatment was effective in this case, destructive cholangitis in dogs may be recoverable with long-term supportive therapies.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21325741/