Peer-reviewed veterinary case report
Dog with liver cancer and aortic body tumor found after death
By Sterczer, Agnes et al.·Published in Acta veterinaria Hungarica·2011·Department and Clinic of Internal Medicine·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: A case of synchronous hepatocellular carcinoma and aortic body chemodectoma in a dog - pathological case report.
- Species:
- dog
Plain-English summary
A 14-year-old mixed-breed male dog was found to have two types of tumors: liver cancer and a benign tumor near the heart. In the months leading up to his passing, he showed signs of weakness, loss of appetite, and pain in his abdomen. Unfortunately, the tumors were discovered only during a necropsy after the dog was euthanized. This case is notable because it is the first reported instance of these two tumors occurring together in a dog.
People also search for: dog liver cancer symptoms · mixed-breed dog weakness and loss of appetite · aortic body chemodectoma in dogs
Abstract
The authors describe a case of synchronously occurring (double) tumours, i.e. primary hepatocellular carcinoma and aortic body chemodectoma in a 14-year-old mixed-breed male dog. The tumours were identified during necropsy, following euthanasia. In the last months of its life, the dog showed signs of weakness, anorexia, apathy, inactivity, and abdominal palpation elicited a painful reaction. The primary liver cancer emerged in the left lateral lobe without evidence of any distant metastases. Histopathological and immunohistochemical investigations revealed a well-differentiated, trabecular, claudin-7-, claudin-5- and pancytokeratin-negative hepatocellular carcinoma. The Ki-67 proliferation index was 33%. During necropsy, a synchronously occurring benign, grade I type aortic body chemodectoma was also detected in the dog. This neuroendocrine tumour showed chromogranin-, synaptophysin-, neuron-specific enolase- and S100 protein-positivity, and the Ki-67 proliferation index was 2%. The authors believe that this is the first description of synchronously occurring hepatocellular carcinoma and aortic body chemodectoma in a dog.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21354946/