A Case Report of Hepatosplenomegaly Due to Chronic Salmonellosis in Holstein Calves

Abstract

In this case report, our aim was to present the clinical, macroscopic, bacteriological, and antibiogram results of a chronic salmonellosis case in calves on a dairy farm. A total of 12 Holstein calves weaned at 75-90 days of age on a dairy farm with clinical signs were presented in the case report. The calves displayed intermittent fever, diarrhea, and pneumonia that did not respond to treatment. The most notable finding at necropsy was hepatosplenomegaly. The diagnosis of Salmonella spp. was confirmed from the samples taken from the calves, and antibiograms revealed the resistance to many antibiotics. The disease did not recur following attention to management practices and application of protective hyperimmune serum. The presented case report emphasizes that chronic Salmonella spp. infection may lead to severe losses in calves, highlighting pathological findings, antibiotic resistance, and preventive and management practices.