Peer-reviewed veterinary case report
Cat with acute myeloblastic leukemia treated with chemo
By Mashita, Tadahisa et al.·Published in The Journal of veterinary medical science·2006·Maizuru Animal Medical Center, Japan·View original on PubMed →
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Original publication title: A cat with acute myeloblastic leukemia without maturation (M1) treated with combination chemotherapy.
- Species:
- cat
Plain-English summary
A 2-year-old domestic shorthair cat was brought in because it was less active and not eating. Tests showed the cat had a type of blood cancer called acute myeloblastic leukemia (M1), which was causing low red blood cells and high levels of immature white blood cells. The vet started chemotherapy with several medications, but the cat only partially responded to treatment and needed multiple blood transfusions. Sadly, the cat passed away 14 weeks after the initial visit.
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Abstract
A 2-year-old domestic shorthair cat was presented to us with decreased activity and anorexia. Hematologic findings revealed a mild non-regenerative anemia, thrombocytopenia, and leukocytosis with an increase in blast cells. Bone marrow aspirates also revealed a marked increase of blasts. The blastic cells were shown to be positive for peroxidase. Acute myeloblastic leukemia without maturation (M1) was diagnosed according to the FAB classification. Chemotherapy was initiated with cyclophosphamide, vincristine, prednisolone, and cytosine arabinoside. The cat responded partially. In total, the cats were given 7 blood transfusions. The cat died 14 weeks after first being presented to us.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16462128/