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Peer-reviewed veterinary case report

A chronic wasting syndrome in a horse associated with granulomatous enteritis.

Journal:
Journal of the South African Veterinary Association
Year:
1978
Authors:
Bester, R C & Coetzer, J A
Species:
horse

Plain-English summary

A 2-year-old Thoroughbred colt was diagnosed with a condition called granulomatous enteritis, which means there was inflammation in his intestines. The horse was losing weight and had swelling under his skin, especially on his belly and legs. When examined, the walls of his intestines were found to be thicker than normal, and under a microscope, there were signs of immune cells infiltrating the intestinal tissue. This inflammation was particularly severe in the muscle layers of the gut. The treatment outcome is not specified in the abstract.

Abstract

A case of granulomatous enteritis in a 2 year-old Thoroughbred colt is reported. Clinically the horse showed chronic wasting and subcutaneous oedema of the ventral parts of the body and legs. Grossly the wall of the jejunum and ileum was uniformly thickened. Microscopically the lamina propria, submucosa and the tunica muscalaris of the small intestine were infiltrated with lymphocytes, plasma cells, epithelioid cells and occasional multinucleated giant cells. The granulomatous reaction was most marked in the muscular layers of the gut wall.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/752085/