Peer-reviewed veterinary case report
Cushing's disease from pituitary cancer in an 8-year-old female dog
By Boujon, C E et al.·Published in Journal of comparative pathology·1991·Institute of Animal Pathology·View original on PubMed →
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Original publication title: A clinico-pathological study of canine Cushing's disease caused by a pituitary carcinoma.
- Species:
- dog
Plain-English summary
An 8-year-old female cocker spaniel was diagnosed with Cushing's disease, which is caused by a tumor in the pituitary gland. The dog showed symptoms typical of this condition, such as excessive thirst and urination. The tumor was identified as a type of cancer that does not respond to certain medications. Unfortunately, the presence of cancer spread within the brain complicated her treatment. The specifics of her treatment and outcome were not detailed, but Cushing's disease can often be managed with medication or surgery, depending on the case.
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Abstract
Knowledge of clinico-pathological correlations in canine Cushing's disease is rather poor. Therefore we describe, clinically and pathologically, a case of pituitary tumour-dependent Cushing's disease in an 8-year old female cocker spaniel. Based on our results, the tumour was defined as a non-dexamethasone-suppressive, corticotrophic adenocarcinoma characterized by some new findings such as intracerebral metastases of anti-ACTH-labelled tumour cells and combined alpha-, beta- and gamma 3-MSH immunoreactivity in the tumour.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1662239/