PetCaseFinder

Peer-reviewed veterinary case report

Safe drug combo to end late pregnancy in dogs

By Corrada, Yanina et al.·Published in Journal of the American Animal Hospital Association·2006·Faculty of Veterinary Medicine·View original on PubMed

PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →

Original publication title: A combination of oral cabergoline and double cloprostenol injections to produce third-quarter gestation termination in the bitch.

Plain-English summary

A group of 22 pregnant dogs, between 35 to 45 days into their pregnancy, were treated with a combination of cabergoline and cloprostenol to see if it could safely terminate their pregnancies. Out of the 13 dogs that received the treatment, 12 aborted within about 5 days, with only mild side effects noted. The remaining dogs in the study continued their pregnancies normally. This combination of medications proved to be an effective and safe option for terminating pregnancies in dogs during the later stages.

People also search for: dog pregnancy termination · cabergoline for dogs · cloprostenol side effects in dogs

Abstract

To assess the efficacy and safety of a combined cabergoline and cloprostenol protocol to terminate third-quarter pregnancy, 22 pregnant bitches that ranged from 35 to 45 days after mating were randomly assigned to a treatment group (n=13) or to an untreated control group (n=9). The animals were monitored for 12 days, and pregnancy termination was confirmed by ultrasound examination. Twelve of the 13 treated bitches aborted within 9 days of the initiation of treatment (mean 4.6 days). Only mild side effects were observed. The control animals had normal gestational courses, as did the bitch that did not respond to the therapy. This combination of drugs appeared to be a practical, safe, and efficient abortifacient when used in third-quarter pregnancies.

Find similar cases for your pet

PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.

Search related cases →

Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16960040/