A Comparison of Modified Radical Mastectomy, Breast Conservation Therapy, and Nipple-sparing Mastectomy With Immediate Implant Reconstruction.

Abstract

<h4>Background</h4>This study evaluated and compared the perioperative outcomes and quality of life associated with modified radical mastectomy (MRM), breast-conserving surgery (BCS), and nipple- and areola-sparing subcutaneous mastectomy with immediate breast reconstruction (NSM-IBR).<h4>Methods</h4>This retrospective cohort study included 105 patients with breast cancer, stratified into MRM (n = 35), BCS (n = 35), and NSM-IBR (n = 35) groups. The perioperative outcomes (operative times, intraoperative blood loss, and recent complications) were subsequently compared across the 3 groups. Differences in patient satisfaction were assessed using the 36-item short form health survey scale 3 months after surgery.<h4>Results</h4>In the NSM-IBR group, the mean operative time was 207.1 ± 38.7 minutes, significantly longer than that in the MRM and BCS groups (<i>P</i> < 0.001). The intraoperative blood loss in the BCS group was significantly lower than in the MRM and NSM-IBR groups (<i>P</i> < 0.05). The total 36-item short form health survey score in the NSM-IBR group was higher than in the BCS and MRM groups (80.03 ± 1.27 versus 54.51 ± 3.35, <i>P</i> < 0.001; 80.03 ± 1.27 versus 78.46 ± 1.42, <i>P</i> = 0.004).<h4>Conclusions</h4>NSM-IBR warrants promotion as a means to enhance the postoperative psychological and physiological health of patients with breast cancer. Surgeons should undergo specialized training to reduce complications associated with the procedural complexity of NSM-IBR.