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Peer-reviewed veterinary case report

A comparison of the effectiveness between amniotic membrane homogenate and transplanted amniotic membrane in healing corneal damage in a rabbit model.

Journal:
Acta ophthalmologica
Year:
2011
Authors:
Guo, Qing et al.
Affiliation:
Department of Life Science and Engineering · China
Species:
rabbit

Abstract

PURPOSE: To determine whether amniotic membrane homogenate is as effective in healing corneal damage as amniotic membrane transplantation in a rabbit model. METHOD: The rabbits were divided into three groups. The cornea of one eye in each rabbit was incised resulting in a defect of approximately 8 mm in diameter. Amniotic membrane transplantation was performed in the first group, and amnion homogenate was administered four times a day in the second group. The third group was the control group. RESULTS: There were no differences in the diameter of the defects and the rate of corneal growth between the amnion transplant group and the amnion homogenate group. CONCLUSION: Amnion homogenate is as effective as transplanted amniotic membrane in promoting corneal healing in a rabbit model.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/21310014/