Peer-reviewed veterinary case report
A core proteome profile unites mouse models and patients in Alzheimer disease.
- Journal:
- Cell reports. Medicine
- Year:
- 2024
- Authors:
- Tsaka, Grigoria et al.
- Affiliation:
- Department of Cellular and Molecular Medicine
Abstract
Levites et al. demonstrate that mouse models of Alzheimer disease (AD), exhibiting amyloid-beta (Αβ) plaque formation, share Αβ responsome proteins with humans. Their work underscores the value of these models in studying Αβ aggregation, cellular vulnerability, and early-stage AD pathology.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/39168096/