Peer-reviewed veterinary case report
Dog with a rare mixed skin tumor affecting hair follicles and glands
By Watanabe, Ken-Ichi et al.·Published in The Journal of veterinary medical science·2017·Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: A cutaneous mixed tumor in a dog.
- Species:
- dog
Plain-English summary
A 9-year-old mixed breed female dog was found to have a skin tumor that was well-defined and made up of different types of cells. The tumor had features from hair follicles and sweat glands, which led to its diagnosis as a cutaneous mixed tumor. While the abstract does not specify treatment details or outcomes, these tumors can often be surgically removed. If your dog has a similar skin growth, it's important to consult your veterinarian for an evaluation and potential treatment options.
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Abstract
The atypical cutaneous tumor of a 9-year-old mixed breed female dog was examined. The tumor was well-demarcated and histologically composed of a trichoblastic area, tricholemmal area and apocrine glandular area. Neoplastic cells in trichoblastic area and tricholemmal area had PAS-positive granules in the cytoplasm and were positive for pan-cytokeratin, cytokeratin 5/6, 14 and 19 and p63. Neoplastic cells in trichoblastic area were also positive for cytokeratin 15 and CD34. Neoplastic cells in apocrine glandular area were positive for pan-cytokeratin and cytokeratin 7, 18 and 19. Myoepithelial cell proliferation with osteocartilaginous metaplasia was observed in this area. Since neoplastic cells showed multiphenotypic differentiation for hair follicles and apocrine glands, the present case was diagnosed as a cutaneous mixed tumor.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28132963/