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Peer-reviewed veterinary case report

A field evaluation of an isothermal DNA amplification assay for the detection of Theileria annulata infection in cattle.

Journal:
Molecular and cellular probes
Year:
2017
Authors:
Gomes, Jacinto et al.
Affiliation:
Unidade Estrat&#xe9

Abstract

A loop-mediated isothermal amplification (LAMP) assay was evaluated for the detection of Theileria annulata infection in cattle. The results were compared with a real-time PCR used for the quantification of T. annulata parasitaemia. One hundred bovine blood samples from 16 cattle farms were tested with LAMP and real-time PCR, with T. annulata DNA being detected in 66% and 67% of the samples, respectively. The results showed that the LAMP assay detects a parasitaemia as low as 0.00025%, indicating a high analytical sensitivity of LAMP for clinical diagnosis of bovine theileriosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/28013043/