Peer-reviewed veterinary case report
Does lufenuron pre-treatment help treat fungal skin infections in cats
By Mancianti, Francesca et al.·Published in Journal of feline medicine and surgery·2009·University of Pisa, Italy·View original on PubMed →
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Original publication title: A lufenuron pre-treatment may enhance the effects of enilconazole or griseofulvin in feline dermatophytosis?
- Species:
- cat
Plain-English summary
A group of 25 cats with a skin infection caused by a fungus called Microsporum canis were treated to see if a medication called lufenuron could help improve the effectiveness of two other antifungal treatments, enilconazole and griseofulvin. The cats that received lufenuron before the other treatments showed no signs of infection and were considered cured after 150 days. While lufenuron alone didn't work against the infection, it may help boost the immune response when used alongside other medications. More research is needed to confirm how well lufenuron can support these treatments for stubborn infections.
People also search for: cat skin infection treatment · lufenuron for cats · griseofulvin dosage for cats
Abstract
The effectiveness of enilconazole (4 weekly rinses with a 0.2% solution) or griseofulvin (50mg/kg twice daily for 40 days) following a pre-treatment with oral lufenuron (100mg/kg by-weekly for 8 weeks) was tested on 25 (11+14) Microsporum canis infected cats. Control animals were treated with lufenuron, griseofulvin and enilconazole alone. At day 150 pre-treated animals were culturally negative and clinically cured. While lufenuron alone was found to be ineffective against M canis infection, an immunomodulatory effect of the drug can be suggested, as reported in literature. Its use could be reserved to long-lasting infections, unsuccessfully treated with conventional drugs. Further studies are required to clearly establish the possible adjuvant effect of this molecule when used prior to enilconazole or griseofulvin.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18684653/