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Peer-reviewed veterinary case report

A lysosomal fluorescent probe for the imaging of viscosity in tumoral ferroptosis and rheumatoid arthritis mice models.

Journal:
Chemical communications (Cambridge, England)
Year:
2025
Authors:
Wang, Hui et al.
Affiliation:
Institute of Environmental Science · China
Species:
rodent

Abstract

Viscosity, as an important micro-environment parameter, is closely related to the occurrence and progression of various diseases. Herein, we have developed a novel fluorescent probe (BIB) for lysosomal viscosity detection. Interestingly, using BIB,imaging of viscosity fluctuations in tumoral ferroptosis and rheumatoid arthritis models has been successfully achieved.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/40719005/