Peer-reviewed veterinary case report
Moisturizer with glycerol helps dog skin heal faster after damage
By Panzuti, Pauline et al.·Published in Veterinary dermatology·2020·VetAgro Sup, France·View original on PubMed →
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Original publication title: A moisturizer formulated with glycerol and propylene glycol accelerates the recovery of skin barrier function after experimental disruption in dogs.
- Species:
- dog
Plain-English summary
A group of six healthy beagle dogs had their skin barrier disrupted to test how well a moisturizer could help it recover. The dogs received a moisturizer containing glycerol and propylene glycol applied twice daily for a week on one side of their bodies, while the other side was left untreated. After treatment, the side with the moisturizer showed less water loss from the skin and improved skin thickness, indicating better barrier function. This suggests that using a moisturizer could be beneficial for dogs with skin issues like atopic dermatitis.
People also search for: dog skin problems moisturizer · beagle skin care · atopic dermatitis treatment for dogs
Abstract
BACKGROUND: Moisturizers are foundational therapies for human atopic dermatitis. In veterinary medicine, the use of moisturizers has been recommended by an expert committee to alleviate skin dryness that would occur, for example, in canine atopic dermatitis (cAD). However, little is known regarding the effects of moisturizers on the skin barrier. HYPOTHESIS/OBJECTIVES: To investigate the effects of a moisturizer on skin barrier recovery in a canine model of chronic mechanical barrier disruption. ANIMALS: Six healthy beagle dogs maintained in a laboratory setting. METHODS AND MATERIALS: A model of chronic skin barrier disruption was simulated by tape stripping on both sides of the thorax. The moisturizer then was applied twice daily for one week to one side of the thorax, while the other hemithorax was left untreated. The effects were evaluated by measurement of transepidermal water loss (TEWL) at various times during skin barrier recovery, and by histological assessment of the disrupted skin one week after moisturizer application. RESULTS: Overall, TEWL was reduced, epidermal thickness was lower, stratum corneum thickness was greater and the intensity of the dermal inflammatory infiltrate was reduced for treated sites. CONCLUSIONS AND CLINICAL IMPORTANCE: These results suggest a potential benefit of the moisturizer for improving skin barrier function, which is frequently altered in chronic inflammatory dermatoses such as cAD.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32628309/