Peer-reviewed veterinary case report
A mouse model to test the anti-inflammatory effect of facultative anaerobes on dextran sulfate sodium-induced colitis.
- Journal:
- STAR protocols
- Year:
- 2023
- Authors:
- Yu, Kaiyuan et al.
- Affiliation:
- Tianjin Institute of Immunology · China
Abstract
The role of facultative anaerobic bacteria in colitis remains to be elucidated. We have adapted a mouse model to explore the effect of individual facultative anaerobic bacteria on colitis, focusing on adapting a cocktail of antibiotics and multiple instillations by gavage. Weight, disease activity index, colon length, and histological score are used to assess the severity of colitis. We also describe anaerobic processing protocols of preparing facultative anaerobes. For complete details on the use and execution of this protocol, please refer to Li et al. (2022)..
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/36602904/