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Peer-reviewed veterinary case report

Probiotics helped puppies recover faster from diarrhea in study

By Molina, Rosa A et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2023·Centro de Referencia para Lactobacilos (CERELA)·View original on PubMed

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Original publication title: A multi-strain probiotic promoted recovery of puppies from gastroenteritis in a randomized, double-blind, placebo-controlled study.

Species:
dog

Plain-English summary

A group of 120 puppies aged 1 to 4 months with diarrhea caused by gastroenteritis were treated with a multi-strain probiotic for a week. The puppies receiving the probiotic showed significant improvement, with many achieving normal stool consistency compared to those who received a placebo. By the end of the treatment, about 70% of the puppies on the probiotic had an excellent recovery, while only a small percentage of the placebo group showed similar results. This suggests that probiotics can help puppies recover faster from diarrhea.

People also search for: puppy diarrhea treatment · probiotics for puppies · gastroenteritis in dogs · how to help puppy with diarrhea

Abstract

OBJECTIVE AND ANIMALS: Acute diarrhea is among the most common causes of veterinary consultations for dogs. A double-blind, placebocontrolled intervention trial was done with 120 puppies with gastroenteritis. These dogs were 1 to 4 mo old, male and female, of various breeds and sizes. PROCEDURE: Dogs were randomly allocated into 2 groups: Those in the treated group (TG) received a multi-strain probiotic withCRL1693,CRL1695,CRL1696, andCRL1702 (1 &#xd7; 10CFU/mL) daily for 7 d, whereas those in the control group (CG) received a placebo. All puppies received intravenous fluids, an antiparasitic, amoxicillin PO, and enrofloxacin SC. RESULTS: At the start of the trial, the 2 groups were similar. Probiotic administration for 7 d normalized fecal consistency, with 69, 50, and 80% of small, medium, and large puppies in the TG achieving a fecal score of 1 (separate hard lumps) at 7 d, significantly better than puppies in the CG. After 7 d of treatment, most puppies (70%) in the TG had an excellent recovery, whereas in the CG, recoveries were 35.7% "bad" and 30.4% "fair." Therefore, treatment with probiotics hastened recovery (< 0.0001). At the end of the trial, there was a significant increase of cultivable lactobacilli in the feces of TG puppies, but no significant differences between the 2 groups in numbers of total mesophylls, enterobacteria, or Gram-positive cocci. Total mortality was 5.8%, including 4 puppies from the CG and 3 from the TG. CONCLUSION: In a randomized, double-blind, placebo-controlled study, puppies with gastroenteritis symptoms receiving a multi-strain probiotic had rapid improvement, implying beneficial effects on the microbiota and its functionality.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37397694/