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Peer-reviewed veterinary case report

A new inducible mouse model of FH loss.

Journal:
Methods in cell biology
Year:
2026
Authors:
Zecchini, Vincent et al.
Affiliation:
Hutchison-MRC Research Institute · United Kingdom

Abstract

Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) is a rare autosomal dominant disorder that is characterized by the development of multiple cutaneous and uterine leiomyomas and predisposes individuals to an aggressive and highly metastatic form of Renal Cell Cancer (RCC).

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41724571/