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Peer-reviewed veterinary case report

A new recombinant F1 antigen as a cost and time-effective tool for plague diagnosis.

Journal:
Journal of microbiological methods
Year:
2020
Authors:
Tavares, Diego H C et al.
Affiliation:
Departamento de Microbiologia - Instituto Aggeu Magalh&#xe3 · Brazil

Abstract

The Yersinia pestis capsular antigen F1 is widely used in plague laboratory diagnosis. Here, we describe the production of an F1 recombinant protein within reduced time and biosafety requirements. Its evaluation in hemagglutination tests indicated that the recombinant F1 can replace the conventional F1 protein for plague diagnosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/32229265/