Peer-reviewed veterinary case report
Fluconazole works as well as ketoconazole for treating Malassezia
By Sickafoose, L et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2010·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: A noninferiority clinical trial comparing fluconazole and ketoconazole in combination with cephalexin for the treatment of dogs with Malassezia dermatitis.
- Species:
- dog
Plain-English summary
A group of dogs with Malassezia dermatitis, a skin condition caused by yeast, were treated with either fluconazole or ketoconazole along with cephalexin for any bacterial infection. Both treatments significantly reduced the yeast count and improved symptoms like itching. The results showed that fluconazole worked just as well as ketoconazole, meaning pet owners can consider either option for their dogs with this skin issue.
People also search for: dog skin problems treatment · fluconazole for dogs · Malassezia dermatitis in dogs · dog itching relief · ketoconazole for dog skin issues
Abstract
This double-blinded noninferiority clinical trial evaluated the use of oral fluconazole for the treatment of Malassezia dermatitis in dogs by comparing it with use of an accepted therapeutic agent, ketoconazole. Dogs presenting with Malassezia dermatitis were treated with either fluconazole or ketoconazole in addition to cephalexin for concurrent bacterial dermatitis. Statistically significant improvements in cytologic yeast count, clinical signs associated with Malassezia dermatitis, and pruritus were seen with both antifungal treatments. There was no statistical difference between the treatments with regard to the magnitude of reduction in these parameters. These results suggest that fluconazole is at least as effective as ketoconazole for the treatment of dogs with Malassezia dermatitis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20957617/