Peer-reviewed veterinary case report
Local antibiotic hydrogel used after dog knee surgery infection
By Reed, Travis P et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2016·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: A novel dextran polymer hydrogel local antimicrobial therapy in dogs: A pilot study.
- Species:
- dog
Plain-English summary
A group of 20 dogs that had surgery to remove implants from their knees due to suspected infections were treated with a new antimicrobial gel made from a dextran polymer. This gel, which contained antibiotics amikacin and clindamycin, was applied directly to the surgery site without using any systemic antibiotics. After 12 weeks, none of the dogs showed signs of infection or inflammation, and there were no adverse reactions to the gel. This suggests that the new treatment could be a safe and effective option for managing surgical site infections in dogs.
People also search for: dog knee surgery infection treatment · antimicrobial gel for dogs · dog surgery recovery signs
Abstract
Our purpose was to evaluate physical, laboratory, and/or radiographic abnormalities associated with a novel dextran polymer hydrogel local antimicrobial agent impregnated with amikacin and clindamycin in dogs having tibial plateau leveling osteotomy implants removed due to suspected surgical site infection. A total of 28 client-owned dogs were enrolled and 20 completed the study. Routine plate explantation and bacterial cultures were performed and the polymer hydrogel was applied to the surgery site. No systemic antimicrobials were used after surgery. Serum biochemistry, hematology, urinalysis, physical examinations, and radiographs were monitored before surgery and up to 12 wk after surgery. Sixteen of the 20 dogs (80%) had a positive bacterial culture, 44% of which were methicillin resistant. There were no significant alterations of laboratory values, physical examination, or radiographs to indicate adverse reactions to the polymer hydrogel. There were no signs of inflammation or infection in any patient at the 12-week postoperative recheck.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26834272/