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Peer-reviewed veterinary case report

A novel method for evaluating the efficacy of pharmaceuticals against the <i>in vivo</i> stage of <i>Ichthyophthirius multifiliis</i> in fish.

Year:
2025
Authors:
Hu GR et al.
Affiliation:
Institute of Hydrobiology (CAS) · China

Abstract

This study presents a description of a novel apparatus for evaluating the efficacy of pharmaceuticals against the <i>in vivo</i> stage of the fish parasite <i>Ichthyophthirius multifiliis</i>. The apparatus comprises a transparent acrylic rectangular cuboid, a metal wire mesh, and a gridded black acrylic bottom plate. Fallen trophonts are caught on the bottom plate and are separated from the fish by the mesh. The efficacy of a pharmaceutical can be assessed by adding it to the aquarium and subsequently counting the number of live tomonts and differntiating rate on the bottom plate. This device facilitates observation and enhances the precision and accuracy of pharmaceutical evaluation experiments.

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Original publication: https://europepmc.org/article/MED/40808758