Peer-reviewed veterinary case report
Pantropic canine coronavirus strain 450/07 causes diarrhea
By Decaro, Nicola et al.·Published in Veterinary microbiology·2012·Department of Veterinary Public Health, Italy·View original on PubMed →
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Original publication title: A pantropic canine coronavirus genetically related to the prototype isolate CB/05.
- Species:
- dog
Plain-English summary
A 60-day-old miniature pinscher sadly died after being infected with a new strain of canine coronavirus. This virus caused symptoms like diarrhea and a drop in white blood cells, which can weaken the immune system. Most of the infected puppies showed signs of illness, but the disease was generally mild. The virus was found in their feces and internal organs, indicating it can spread beyond the gut. Unfortunately, despite the findings, the specific treatment for this strain wasn't detailed, but it highlights the importance of monitoring for symptoms in young dogs.
People also search for: puppy diarrhea treatment · canine coronavirus symptoms · miniature pinscher health issues
Abstract
We report the genetic and biological characterisation of a novel pantropic canine coronavirus (CCoV), strain 450/07, which caused the death of a 60-day-old miniature pinscher. At the genetic level, this virus was strictly related to the prototype strain CB/05, but displayed some unique features. After experimental infection with the new pantropic isolate, most inoculated dogs showed diarrhoea and acute lymphopenia. Gross lesions and histological changes were mainly evident in the gut and lymphoid tissues, although some animals showed remarkable changed also in parenchymatous organs. The viral RNA was detected in the faeces and/or internal organs of most pups. These findings seem to indicate that strain 450/07 is able to spread to internal organs (mainly lymphoid tissues), causing lymphopenia but inducing a mild disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22542271/