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Peer-reviewed veterinary case report

Muscle weakness and wasting in young male Labrador retrievers

By Cosford, Kevin L et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2008·Department of Small Animal Clinical Sciences, Canada·View original on PubMed

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Original publication title: A possible new inherited myopathy in a young Labrador retriever.

Species:
dog
Movement & jointsDogs

Plain-English summary

A 5-month-old male Labrador retriever was brought to the vet because he was getting weaker and losing muscle mass. Tests on his muscle tissue showed changes similar to a type of inherited muscle disease seen in Great Danes. This condition also affected several of his male littermates and half-siblings, suggesting it might be genetic. Unfortunately, the study does not mention any specific treatments or outcomes for this puppy.

People also search for: Labrador retriever muscle weakness · inherited myopathy in dogs · puppy muscle atrophy causes

Abstract

A 5-month-old, male, Labrador retriever was evaluated for progressive weakness and muscle atrophy. Histologic evaluation of fresh frozen muscle revealed distinct cytoarchitectural changes and central mitochondrial accumulations indistinguishable from those found in the inherited myopathy described in Great Danes. Multiple male littermates and half-siblings were similarly affected.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18481550/