Peer-reviewed veterinary case report
Combination antibiotic treatment and CRP levels in dogs with Babesia
By Suzuki, Koretoki et al.·Published in The Journal of veterinary medical science·2007·Faculty of Agriculture, Japan·View original on PubMed →
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Original publication title: A Possible treatment strategy and clinical factors to estimate the treatment response in Bebesia gibsoni infection.
- Species:
- dog
Plain-English summary
Four dogs with a serious blood infection caused by Babesia gibsoni were treated with a combination of three medications: clindamycin, metronidazole, and doxycycline. This treatment worked well for three of the dogs, clearing the infection from their blood, while one dog experienced a relapse after initially improving. The study also found that monitoring a protein called C-reactive protein (CRP) could help vets gauge how well the treatment is working, as CRP levels dropped as the dogs began to recover.
People also search for: dog Babesia gibsoni treatment · canine babesiosis symptoms · CRP levels in dogs
Abstract
The effectiveness of combination therapy using clindamycin, metronidazole and doxycycline against canine babesiosis, and the usefulness of platelet count and the plasma C-reactive protein (CRP) concentration as an estimation factor for treatment, were evaluated in four dogs experimentally infected with Babesia gibsoni. The combination therapy successfully eliminated B. gibsoni in peripheral blood in 3 of 4 dogs, however the remaining dog showed obvious uncontrolled relapse after a temporary recovery. In addition, it was shown that CRP levels decreased in an inverse relationship to the recovery of packed cell volume and therefore CRP levels could be used as an optional clinical marker to estimate the response to treatment.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17551236/