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Peer-reviewed veterinary case report

Detecting Onchocerca lupi eye infection in dogs with ELISA test

By Giannelli, Alessio et al.·Published in Parasitology research·2014·Dipartimento di Medicina Veterinaria, Italy·View original on PubMed

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Original publication title: A preliminary investigation of serological tools for the detection of Onchocerca lupi infection in dogs.

Species:
dog

Plain-English summary

A dog with eye problems was studied to see if a specific blood test could detect an infection caused by Onchocerca lupi, a parasite that can lead to nodular lesions and serious eye issues. This parasite is becoming more recognized for its potential to affect both dogs and humans. The researchers looked at a commercial test designed to find O. lupi antigens in dog blood samples. While the study was preliminary, it highlighted the need for effective diagnostic tools to identify this infection in dogs, which could help in larger studies in the future.

People also search for: dog eye problems · Onchocerca lupi infection in dogs · dog blood test for parasites

Abstract

Onchocerca lupi is a neglected filarioid causing nodular lesions associated with acute or chronic ocular disease in dogs. Despite the recent appraisal of its zoonotic potential, human cases are increasingly reported in the Old and New Worlds. Therefore, the development of accurate tools for the rapid diagnosis of O. lupi infections in dogs is becoming a priority. In this study, we conducted a preliminary investigation aimed at evaluating the usefulness of a commercially available ELISA test for the detection of O. lupi antigens in canine sera. The potential use of this tool for larger epidemiological studies of canine onchocerciasis is discussed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24647986/