Peer-reviewed veterinary case report
A preliminary study of direct application of atelocollagen into a wound lesion in the dog cornea.
- Journal:
- Current eye research
- Year:
- 2008
- Authors:
- Nagayasu, Aya et al.
- Affiliation:
- Department of Veterinary Anatomy · Japan
- Species:
- dog
Abstract
PURPOSE: To evaluate the effectiveness of atelocollagen for canine corneal wound healing. MATERIALS AND METHODS: Atelocollagen was used to fill a transplant bed in the central cornea, which was then covered with a contact lens. The wound healing process was analyzed clinically, morphologically, and biochemically. RESULTS: At the early healing stage, both the pupillary zone and details of the iris were observed. The stromal collagen fibrils normalized in a time-dependent manner. Type III collagen in the wound area was detected faintly throughout the experimental period. CONCLUSIONS: This novel method is advantageous for accelerating wound healing without causing inflammation.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18798076/