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Peer-reviewed veterinary case report

A protein regulated by UBE3A PEGs a potential biomarker.

Journal:
Cell reports. Medicine
Year:
2021
Authors:
Germain, Noelle D & Chamberlain, Stormy J
Affiliation:
Department of Genetics and Genome Sciences · United States

Abstract

New research from Pandya and colleaguesidentifies PEG10 as a UBE3A-regulated protein that may underlie pathophysiology in Angelman syndrome neurons. PEG10 is a secreted protein, and this work suggests that it may be a potential biomarker for Angelman syndrome therapeutics under development.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/34467252/