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Peer-reviewed veterinary case report

Dog with rare vagus nerve tumor causing multiple nerve problems

By Giraud, Lucile et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2020·CHV Fr&#xe9, France·View original on PubMed

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Original publication title: A rare case of malignant vagus nerve sheath tumor presenting with multiple cranial nerve dysfunction in a dog.

Species:
dog

Plain-English summary

A 5-year-old male Gascon Saintongeois dog was brought to the vet after experiencing coughing, difficulty swallowing, and signs of a neurological issue, including problems with balance. After imaging tests, the vet discovered a tumor affecting the vagus nerve, which was pressing on the brainstem and causing multiple nerve problems. The tumor was identified as a malignant nerve sheath tumor, a rare and aggressive type of cancer. Unfortunately, due to the severity of the condition, treatment options may be limited, and the prognosis can be serious.

People also search for: dog coughing and swallowing problems · Gascon Saintongeois dog brain tumor · treatment for dog nerve sheath tumor

Abstract

A 5-year-old intact male Gascon Saintongeois dog was presented with a 6-month history of coughing, laryngeal paralysis, a deglutition disorder of gradual onset, and left-sided Horner's syndrome. The dog was admitted as an emergency for acute central vestibular signs. Magnetic resonance images identified a left extra-axial brainstem lesion extending caudally from the medulla to the vagosympathetic trunk. Histological and immunohistological examination revealed a high grade epithelioid malignant peripheral nerve sheath tumor (MPNST). This case report is the first description of a MPNST of the vagus nerve compressing the brainstem and causing multiple cranial nerve dysfunction in a dog. Key clinical message: Nerve sheath tumors have been reported in many locations arising from spinal nerve roots and cranial nerves. Although the trigeminal nerve is the most commonly affected nerve, other cranial nerves such as the vagus can be affected.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33012818/