Peer-reviewed veterinary case report
A real-time polymerase chain reaction for the detection of Streptococcus pneumoniae in blood using a mouse model: a potential new "gold standard".
- Journal:
- Diagnostic microbiology and infectious disease
- Year:
- 2008
- Authors:
- Rouphael, Nadine G et al.
- Affiliation:
- Meningitis and Vaccine-Preventable Diseases Branch · United States
Abstract
Better diagnostics for pneumococcal disease are urgently needed. In a murine model, real-time polymerase chain reaction was superior to conventional culture in detecting pneumococcus in blood, particularly in early disease and after antibiotic administration, and could distinguish between commensalism and infection.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18621498/