Peer-reviewed veterinary case report
Anti-inflammatory drugs and 30-day survival in dogs with lung
By Walton, Rebecca A L et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2017·College of Veterinary Medicine·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: A retrospective study of anti-inflammatory use in dogs with pulmonary blastomycosis: 139 cases (2002-2012).
- Species:
- dog
Plain-English summary
A group of 139 dogs diagnosed with pulmonary blastomycosis, a serious fungal infection affecting the lungs, were treated at a veterinary hospital. Despite receiving various anti-inflammatory medications, such as NSAIDs and corticosteroids, these treatments did not improve the chances of surviving for 30 days. However, dogs that required supplemental oxygen had a much lower survival rate. Overall, while anti-inflammatory drugs didn't help, needing extra oxygen was a significant concern for these dogs' survival.
People also search for: dog pulmonary blastomycosis treatment · dog breathing problems oxygen · anti-inflammatory medication for dogs
Abstract
OBJECTIVE: To determine the effect of anti-inflammatory medications on 30-day survival of dogs treated for pulmonary blastomycosis. DESIGN: Retrospective study. SETTING: University teaching hospital. ANIMALS: One hundred thirty nine client-owned dogs with confirmed pulmonary blastomycosis. MEASUREMENTS AND MAIN RESULTS: The medical records of dogs diagnosed with pulmonary blastomycosis between May 2002 and October 2012 were identified. Of 139 dogs, 85 (61%) survived to 30 days, 38 (27%) were euthanized due to progressive clinical disease, 13 (10%) died secondary to respiratory or cardiac arrest, and 3 (2%) did not survive to 30 days but had an unknown cause of death. Cases were classified based on the anti-inflammatory therapy that was used: nonsteroidal anti-inflammatory drugs (NSAID), corticosteroids, both, or none. Controlling for the effects of itraconazole dose, sex, age, and pretreatment with anti-inflammatory medication, the odds for survival to 30 days was not statistically different between dogs who received no anti-inflammatory medication and the dogs who received NSAIDs (P = 0.86), corticosteroids (P = 0.65), or both (P = 0.27). The need for supplemental oxygen was associated with decreased survival (P < 0.0001). CONCLUSIONS: In this population of dogs with pulmonary blastomycosis, the use of anti-inflammatory medications during therapy did not impact 30-day survival; however, the need for oxygen supplementation was associated with significantly lower survival.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28561957/